Are bio-based and biodegradable microplastics impacting for blue mussel (Mytilus edulis)?

The substitution of petrochemical plastics by bio-based and biodegradable are in need an evaluation for the potential toxic impacts that they can have on marine wildlife. This study aims to assess toxicological effects polylactic acid microparticles at two concentrations, 10 100 ?g/L, during 8 days blue mussel, Mytilus edulis. No significant oxidative stress (catalase, glutathione-S-transferase superoxide dismutase activities), neurotoxicity (acetylcholinesterase), or immunotoxicity (lysosomal membrane stability phosphatase activity) were detectable. multivariate analysis metabolomic data allowed us differentiate individuals according exposure. From loading plot OPLS-DA, 48 ions down-regulated exposed microplastics. They identified based HRMS as glycerophospholipids.